Table 2.

Treatment-emergent adverse events reported in ≥10% of patients regardless of the cause

Adverse event (N = 42)	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Fatigue	5 (12)	14 (33)	5 (12)	0	0
Diarrhea	7 (17)	4 (10)	4 (10)	0	0
Muscle spasms	8 (19)	3 (7)	1 (2)	0	0
Nausea	8 (19)	3 (7)	0	0	0
Bruising	6 (14)	4 (10)	0	0	0
Upper respiratory tract infection	3 (7)	5 (12)	0	0	0
Pneumonia	1 (2)	0	4 (10)	1 (2)	1 (2)
Pyrexia	4 (10)	1 (2)	2 (5)	0	0
Headache	3 (7)	2 (5)	2 (5)	0	0
Fall	6 (14)	1 (2)	0	0	0
Cough	4 (10)	2 (5)	0	0	0
Constipation	3 (7)	2 (5)	0	0	0
Dyspnea	4 (10)	0	1 (2)	0	0
Hyperglycemia	1 (2)	1 (2)	3 (7)	0	0
Hypokalemia	0	2 (5)	3 (7)	0	0
Peripheral edema	1 (2)	4 (10)	0	0	0

Data are presented as n (%).