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Downregulation of SIL1 inhibited AKT/mTOR signaling pathway. (A) Western blot image and (B) quantification analysis indicated that siSIL1 reduced the phosphorylation level of AKT and mTOR without affecting protein expression, as well as decreasing expression of the downstream effector p70S6K. Protein expression was normalized to siNC group.
Note: *P<0.05.
