Table 2.
response rates by RECIST 1.1 criteria
| a. Best overall and hepatic response in entire patient population | ||||
|---|---|---|---|---|
| N = Percentage | N = Percentage | |||
| Overall | Hepatic | |||
| CR | 2 | 3.9% | 3 | 5.9% |
| PR | 22 | 43.1% | 22 | 43.1% |
| SD | 19 | 37.2% | 19 | 37.2% |
| >3 months | 16 | 31.3% | 17 | 33.3% |
| >6 months | 10 | 19.6% | 11 | 21.6% |
| PD | 8 | 15.6% | 7 | 13.7% |
| Total assessable patients | 51 | 51 | ||
| b. Best Hepatic Response by disease burden a | ||||
|---|---|---|---|---|
| Low disease burden | High disease burden | |||
| CR/PR | 18 | 51.4% | 7 | 43.7% |
| SD | 11 | 31.4% | 8 | 50.0% |
| PD | 6 | 17.1% | 1 | 6.3% |
| Total assessable patients | 35 | 16 | ||
CR, complete Response; PR, partial response; SD, stable disease; PD, progressive disease.
a
“high“ disease burden implies more than 10 lesions or more than 50% parenchymal involvement.