Table 3.
Adverse event | Any grade N = % | Grade 3‐4 N = % | ||
---|---|---|---|---|
Hematological toxicity | ||||
Anemia | 51 | 100.0% | 15 | 29.4% |
Neutropenia | 22 | 43.1% | 16 | 31.3% |
Thrombocytopenia | 50 | 98.0% | 16 | 31.3% |
Coagulopathic toxicity | ||||
Hemorrhagic Event | 10 | 19.6% | 2 | 3.9% |
Thromboembolic Event | 7 | 13.7% | 6 | 11.8% |
Cardiovascular toxicity | ||||
Any | 11 | 21.6% | 9 | 17.6% |
Arrhythmias | 5 | 9.8% | 4 | 7.8% |
Pulmonary Edema | 3 | 5.9% | 3 | 5.9% |
Cardiac Ischemia | 5 | 9.8% | 5 | 9.8% |
Cerebrovascular event | 2 | 3.9% | 0 | 0.0% |
Late toxicity | ||||
Fatigue | 17 | 33.3% | 1 | 2.0% |
Mucositis | 1 | 2.0% | 0 | 0.0% |
Nausea | 12 | 23.5% | 0 | 0.0% |
Vomiting | 8 | 15.6% | 0 | 0.0% |
Epigastric pain | 6 | 11.8% | 0 | 0.0% |
Transaminitis | 15 | 29.4% | 3 | 5.9% |
Rash | 1 | 2.0% | 0 | 0.0% |
Constipation | 2 | 3.9% | 0 | 0.0% |