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. 2018 Apr 19;23(2):78–87. doi: 10.1111/jns.12262

Figure 1.

JNS-12262-FIG-0001-c

(A) Schematic model for distribution and metabolism of IgG illustrating a “two compartment model.” Note that newly synthesized IgG as well as subcutaneously administered IgG (SCIG) are initially in the extravascular compartment and then move into the intravascular compartment by diffusion and lymphatic circulation. (B) Pharmacokinetics of serum IgG after a dose of IVIG. IVIG, intravenous immunoglobulin; SCIG, subcutaneous immunoglobulin (Bonilla, 2008 ). Copyright 2008. Reprinted with permission from Elsevier.