Table 1.
Anthropometric, clinical, metabolic, and inflammatory variables of the sample according to the genotypic group.
| Variables | rs495366 genotypes | P | |
|---|---|---|---|
| GG (n=174) | A_ (n=192) | ||
| Age (years) | 79.5 ± 9.3 | 79.2 ± 8.3 | 0.745 |
| Male (%) | 32.2 | 28.1 | 0.398 |
| BMI (kg·m−2) | 26.9 ± 4.9 | 26.9 ± 5.1 | 0.841 |
| WC (cm) | 96.3 ± 12.4 | 94.7 ± 11.4 | 0.169 |
| SBP (mm Hg) | 138.8 ± 20.4 | 142.0 ± 21.2 | 0.150 |
| DBP (mm Hg) | 78.1 ± 11.0 | 77.2 ± 11.5 | 0.268 |
| SAH (%) | 76.4 | 76.0 | 0.929 |
| Glucose level (mg·dl−1) | 101.8 ± 22.6 | 105.4 ± 43.0 | 0.659 |
| HbA1c (%) | 6.0 ± 0.9 | 6.1 ± 1.3 | 0.365 |
| DM2 (%) | 25.3 | 21.4 | 0.374 |
| Total cholesterol (mg·dl−1) | 194.4 ± 40.0 | 203.2 ± 84.2 | 0.297 |
| Triglycerides (mg·dl−1) | 131.5 ± 58.8 | 135.3 ± 62.6 | 0.498 |
| HDL-c (mg·dl−1) | 51.7 ± 12.9 | 51.5 ± 13.2 | 0.988 |
| LDL-c (mg·dl−1) | 113.2 ± 34.1 | 115.9 ± 36.2 | 0.407 |
| VLDL-c (mg·dl−1) | 29.3 ± 13.4 | 30.0 ± 13.9 | 0.482 |
| Creatinine clearance (ml·min−1) | 60.3 ± 26.4 | 55.6 ± 24.1 | 0.120 |
| CRP (mg·dl−1) | 1.61 [2.25] | 1.70 [3.10] | 0.636 |
| TSH (mIU·l−1) | 2.16 [2.05] | 2.15 [2.53] | 0.976 |
| TNF | 0.00 [0.60] | 0.00 [0.34] | 0.684 |
| IL12 | 0.00 [8.92] | 0.00 [8.93] | 0.551 |
| IL10 | 0.84 [2.84] | 1.24 [2.94] | 0.599 |
| Sedentary (%) | 59.2 | 63.0 | 0.453 |
| Smoker (%) | 19.5 | 17.2 | 0.561 |
| Right cIMT (mm) | 1.28 ± 0.60 | 1.40 ± 0.66 | 0.087 |
| Left cIMT (mm) | 1.27 ± 0.60 | 1.44 ± 0.64 | 0.041 |
Data are expressed as average ± standard deviation for normally distributed continuous parameters, relative frequencies within genotype for categorical features, and median with the interquartile range in brackets for nonnormally distributed continuous variables. BMI = body mass index; WC = waist circumference; HbA1c = glycated hemoglobin A1c; DM2 = type 2 diabetes mellitus; VLDL-c = very low-density lipoprotein cholesterol; LDL-c = low-density lipoprotein cholesterol; HDL-c = high-density lipoprotein cholesterol; SBP = systolic blood pressure; DBP = diastolic blood pressure; SAH = systemic arterial hypertension; CRP = C-reactive protein; TSH = thyroid-stimulating hormone; cIMT = carotid intima-media thickness.