TABLE 2. Per cent (%) of baseline anti-factor VIII IgG₄ remaining after preanalytical heat treatment of plasma from haemophilia patients with given Nijmegen-Bethesda units (NBU), measured by fluorescence immunoassay in median fluorescence intensity (MFI) ⁷⁸.

		Baseline IgG4 (MFI)	% Remaining at 56°C After		% Remaining at 58°C After
Specimens	NBU		30′	60′	30′	60′
Patient A	1.5	169	104	78	76	47
Patient B	1.6	1919	117	102	83	61
Patient C	19.3	12 596	91	92	100	75
Patient D	1.6	16 563	91	96	95	ND
Patient E	1.1	303	120	147	93	93
Patient F	1.1	1208	115	100	76	65
Patient G	0.5	17 194	80	93	72	39
Patient H	5.4	22 156	92	94	88	79
		Mean	101	100	85*	66*
		Range	80–120	78–147	72–93	39–93

^*Significantly different from original level in paired t test at P < .05; ND, no data.