Table 3.
Grade 3 to 5 Toxicity Profile
| Patients With Grade 3-5 Toxicity | ||
|---|---|---|
| Toxicity | n | % |
| Hematologic | ||
| Thrombocytopenia | 10 | 41.7 |
| Neutropenia | 14 | 58.3 |
| Lymphopenia | 6 | 25.0 |
| Nonhematologic | ||
| Constitutional | ||
| Fatigue | 1 | 4.2 |
| Infectious | ||
| Febrile neutropeniaa | 6 | 25.0 |
| Infection without neutropeniab | 3 | 12.5 |
| Metabolic | ||
| Hypokalemia | 2 | 8.3 |
| Hyponatremia | 1 | 4.2 |
| Hypophosphatemia | 2 | 8.3 |
| Hypocalcemia | 1 | 4.2 |
| Hypoalbuminemia | 1 | 4.2 |
| Dehydration | 2 | 8.3 |
| Neurologic | ||
| Altered mental status | 1 | 4.2 |
| Gastrointestinal | ||
| Hyperbilirubinemia/transaminitis | 3 | 12.5 |
| Nausea/vomiting | 1 | 4.2 |
| Dermatologic | ||
| Rashc | 1 | 4.2 |
| Immune | ||
| GVH | 1 | 4.2 |
a
Febrile neutropenia included 1 case of death (Grade 5) related to infection.
b
Infection without neutropenia included 1 case of disseminated zoster (Grade 3) and 1 case of cholangitis (Grade 3).
c
Rash was biopsy proven erythema nodosum (Grade 3).