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. 2018 Jul 4;18:303. doi: 10.1186/s12879-018-3203-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Real-time RT-PCR assays of GADD34 and XBP1spl mRNAs from monocyte-derived-macrophages from TB patients receiving adjunct therapy with PBA and/or vitD₃ or placebo (18/group) at week 0, week 4 and 8 after therapy. Data are normalized expression of GAD34 (a) and XBP1spl (b) mRNAs presented as means ± standard deviation. The results showed that PBA and vitD₃ groups showed a significant reduction in expression of ER stress gene spliced XBP1 mRNA at week 8 compared to placebo