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. 2018 Jul 4;20:64. doi: 10.1186/s13058-018-0978-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Validation of single-sample predictors (SSPs) in our validation cohort (a) and two publicly available datasets (b and c). The analysis was performed with data stratified for estrogen receptor (ER) status and adjuvant radiotherapy (RT). The endpoint was ipsilateral breast tumor recurrence (IBTR) and the SSPs were evaluated by survival analysis using the Kaplan-Meier method and log-rank test, and receiver operating characteristics (ROC) analysis with area under the curve (AUC) as a measurement of performance