Longitudinal section through the injury epicenter after injection of PRV into the transplant (A). The discrete injection site is denoted with a yellow arrow. A high degree of PRV-positive cells (indicated with red arrows) can be seen within the transplant (C), demonstrating the high degree of interconnectivity between grafted neurons. PRV labeling of host neurons is seen throughout the cervical spinal cord, from C1 (B) through C7 (D). In addition, labeling is seen within various nuclei in the brainstem (E), including the reticular nucleus (F). Orientation is rostrocaudal (left to right, A–D), dorsal ventral (top to bottom, E and F), and scales are as indicated. PRV, pseudorabies virus. Color image is available online at www.liebertpub.com/neu