Figure 3.
LocusZoom plot of SNPs by chromosome position against −log10P value for their genetic associations with the IBD phenotype. Conditional regional plot for the HLA locus (chr6p21) for the IBD phenotype shows SNPs reaching GWS conditioned on SNP rs9270299 from UC analysis. The top SNP is highlighted in purple. The surrounding SNPs, shown within 500 kb of the top SNP are color-coded to reflect their linkage disequilibrium in r2 (see inset key) with the top SNP. Estimated recombination rates are plotted in pale blue to reflect local LD structure on secondary y-axis.