Table 1. Impact of Fabp1/Scp-2/Scp-x gene ablation (TKO) and pair-fed high fat diet (HFD) on liver triacyglycerol.
Male (M) and female (F) wild-type (WT) and Fabp1/Scp-2/Scp-x gene ablated (TKO) mice were pair-fed a control diet (CO) or high-fat diet (HFD) as described in Methods. At the end of the dietary study, the mice were fasted overnight; livers removed/flash frozen and stored at −80°C. Liver triacylglycerol (nmol/mg protein) was determined as described in Methods. Values represent the mean ± SEM (n = 7). By ANOVA, statistically significant differences (P < 0.05) are designated by different lower-case letters (a, b, c).
| Genotype | Diet | Sex | Triacylglycerol (nmol/mg) |
|---|---|---|---|
| Wild-type | Control | Male | 93±3a |
| Wild-type | Control | Female | 94±3a |
| Wild-type | High-Fat | Male | 59±5bc |
| Wild-type | High-Fat | Female | 47±5b |
| TKO | Control | Male | 54±2b |
| TKO | Control | Female | 47±4b |
| TKO | High-Fat | Male | 70±8c |
| TKO | High-Fat | Female | 67±9c |