Table 3. Cox regression analysis for various potential prognostic factors in overall survival.

Variable	Unfavorable/favorable characteristics	No. of Patients	Univariate (U)			Multivariate (M)
			Relative risk	95% confidential interval	P value	Relative risk	95% confidential interval	P value
Grade	3 / 2 / 1	51 / 29 / 9	2.376	1.279 - 4.412	0.0061	1.523	0.735 - 3.156	0.2580
pT	4, 3 / 2, 1	67 / 22	4.297	1.509 - 12.236	0.0063	1.368	0.432 - 4.331	0.5941
pV	1 / 0	78 / 11	2.557	0.890 - 7.347	0.0811	2.753	0.783 - 8.679	0.1144
M	1 / 0	64 / 25	4.224	1.275 - 13.997	0.0184	6.390	1.733 - 23.569	0.0053
Nrf2	high / low	44 / 45	4.671	2.173 - 10.038	< 0.0001	5.160	1.895 - 14.052	0.0013