Figure 1. Treatment of a Krebs-2 solid tumor (winter 2016).

(A) A schedule of injections. Blue arrow corresponds to CP injection, DNA injections are denoted by a red arrow on the schematic. DNA preparation was a mixture of equal amounts of native human DNA and salmon DNA (3 : 5 = cross-linked : native). (B) Dynamics of changes in the tumor size and number of animals with tumor upon treatment of a 0.5 cm³ graft. Data for the following animal groups treated according to the schedule (A) are shown: control, untreated, CP, CP-only; CP+DNA, CP and DNA injected directly into the tumor at a dose of 1 mg/mouse (first injection of 0.5 mg), CP+(DNA+protamine), CP and DNA injections in combination with protamine given intravenously at a dose of 0.1 mg. (C) Dynamics of changes in the tumor size and number of tumor-bearing animals upon treatment of a non-palpable graft. Treatment groups are the same as in (В). (D) An animal with an initial tumor size of 0.5 cm³ (before treatment) and also the animal with complete cure 210 days after the start of treatment (after treatment).