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. 2018 Jun 19;9(47):28547–28560. doi: 10.18632/oncotarget.25558

Table 2. Effective doses of PTC596 for inducing 50% killing (ED50) in p53 wild-type MCL cells expressing either control shRNA or TP53-specific shRNA.

Cell shRNA ED50 (nM)
Z-138 control shRNA graphic file with name oncotarget-09-28547-i001.jpg
TP53-specific shRNA
JVM-2 control shRNA graphic file with name oncotarget-09-28547-i002.jpg
TP53-specific shRNA

ED50, effective concentration inducing 50% killing as measured by annexin V positivity.