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. 2018 Jul 5;13(7):e0199884. doi: 10.1371/journal.pone.0199884

Table 3. ORs main analyses.

Model 1 Model 2
OR (95% CI) Type-III test (p-value) OR (95% CI) Type-III test (p-value)
GA (per increase in group) 1.09 (1.01–1.18) 0.04 0.97 (0.90–1.05) 0.44
Age in years (reference: 24–31 years) 0 1.33 (1.23–1.45) <0.0001 1.34 (1.24–1.46) <0.0001
2–5 1.02 (0.94–1.10) 1.01 (0.93–1.09)
6–11 1.05 (0.98–1.14) 1.05 (0.97–1.13)
12–17 1.17 (1.09–1.26) 1.18 (1.09–1.26)
18–23 0.95 (0.89–1.02) 0.95 (0.89–1.01)
Birth year (reference: 1980–1984) 1985–1989 0.96 (0.88–1.05) <0.0001 0.96 (0.87–1.05) <0.0001
1990–1994 0.98 (0.89–1.06) 1.02 (0.93–1.11)
1995–1999 1.05 (0.96–1.14) 1.21 (1.11–1.31)
2000–2004 1.24 (1.14–1.35) 1.51 (1.38–1.64)
2005–2009 1.89 (1.73–2.06) 2.27 (2.08–2.48)
Age * gestational age (reference: 24–31 years) 0 1.33 (1.23–1.43) <0.0001 1.36 (1.26–1.46) <0.0001
2–5 1.33 (1.24–1.43) 1.36 (1.26–1.46)
6–11 1.14 (1.06–1.22) 1.15 (1.07–1.24)
12–17 1.04 (0.97–1.11) 1.04 (0.98–1.11)
18–23 1.03 (0.97–1.09) 1.04 (0.98–1.10)
Birth year * gestational age (reference: 1980–1984) 1985–1989 1.02 (0.94–1.11) 0.02 1.02 (0.94–1.10) 0.001
1990–1994 1.07 (0.99–1.16) 1.03 (0.95–1.11)
1995–1999 1.10 (1.02–1.19) 1.11 (1.03–1.20)
2000–2004 1.11 (1.03–1.20) 1.10 (1.02–1.19)
2005–2009 1.12 (1.04–1.21) 1.12 (1.04–1.21)
Female sex NA 0.72 (0.72–0.73) <0.0001
Small for gestational age NA 1.09 (1.06–1.12) <0.0001
Maternal atopy medication NA 1.37 (1.35–1.38) <0.0001
Maternal asthma medication NA 5.57 (5.48–5.65) <0.0001
Maternal educational level (reference: ISCED 0–2) ISCED 3–4 NA 1.00 (0.99–1.01) <0.0001
ISCED 5–8 0.94 (0.93–0.95)
Cesarean section NA 1.13 (1.12–1.15) <0.0001
First born NA 1.03 (1.02–1.04) <0.0001
Acute neonatal respiratory disease NA 1.24 (1.21–1.28) <0.0001
BPD NA 1.44 (1.28–1.63) <0.0001

Estimates are adjusted for the other variables in the model.

OR: odds-ratio

95% CI: 95% confidence interval

NA: not applicable (not included in model)

*: interaction between separate links.