Table 1. Clinicopathological characteristics of colorectal cancer patients according to FUT8 expression.
| Total (n = 318) |
FUT8 protein expression | ||||||
|---|---|---|---|---|---|---|---|
| Low | High | P | |||||
| n = 70 (22.0%) | n = 248 (78.0%) | ||||||
| Age | Mean±SD | 67.0±11.7 | 65.6±12.0 | 67.3±11.7 | 0.273 | ||
| Gender | 0.494 | ||||||
| Male | 188 | 44 | (62.9%) | 144 | (58.1%) | ||
| Female | 130 | 26 | (37.1%) | 104 | (41.9%) | ||
| Tumor location | 0.363 | ||||||
| Proximal colon | 100 | 25 | (35.7%) | 75 | (30.2%) | ||
| Distal colon | 97 | 21 | (30.0%) | 76 | (30.6%) | ||
| Rectum | 121 | 24 | (34.3%) | 97 | (39.1%) | ||
| Histological differentiation | 0.705 | ||||||
| Well | 152 | 37 | (51.4%) | 116 | (46.8%) | ||
| Moderately | 152 | 29 | (41.4%) | 123 | (49.6%) | ||
| Poorly | 14 | 5 | (7.1%) | 9 | (3.6%) | ||
| Stage (UICC) | 0.821 | ||||||
| I | 62 | 16 | (22.9%) | 46 | (18.5%) | ||
| II | 122 | 22 | (31.4%) | 100 | (40.3%) | ||
| III | 89 | 25 | (35.7%) | 64 | (25.8%) | ||
| IV | 45 | 7 | (10.0%) | 38 | (15.3%) | ||
| Tumor invasion | 0.388 | ||||||
| T1 | 33 | 6 | (8.6%) | 27 | (10.9%) | ||
| T2 | 49 | 14 | (20.0%) | 35 | (14.1%) | ||
| T3 | 138 | 32 | (45.7%) | 106 | (42.7%) | ||
| T4 | 98 | 18 | (25.7%) | 80 | (32.3%) | ||
| Lymph node metastasis | 0.211 | ||||||
| Absent | 196 | 39 | (55.7%) | 157 | (63.3%) | ||
| Present | 119 | 31 | (44.3%) | 88 | (35.5%) | ||
| Not available | 3 | 0 | (0.0%) | 3 | (1.2%) | ||
| Distant metastasis | 0.333 | ||||||
| Absent | 273 | 63 | (90.0%) | 210 | (84.7%) | ||
| Present | 45 | 7 | (10.0%) | 38 | (15.3%) | ||
| p53 immunohistochemistry | 1.000 | ||||||
| Negative | 100 | 24 | (34.3%) | 76 | (30.6%) | ||
| Positive | 96 | 24 | (34.3%) | 72 | (29.0%) | ||
| Not available | 122 | 22 | (31.4%) | 100 | (40.3%) | ||