Table 1.

Characteristics of CSCANS Cohort, by level of Muscle Radiodensity

			Muscle radiodensity
	Total n=3,262 N	Mean SMD	N	Low n=966 Row%	N	Normal n=2,296 Row%	pvalue
Overall			27.3 (5.7–35.5)		44.0 (32.5–72.1)
Gender
Men	1634	40.6	463	28.3	1171	71.7	0.11
Women	1628	37.5	503	30.9	1125	69.1
Age at diagnosis
<50	432	47.9	23	5.3	409	94.7	<0.0001
50–<60	806	42.3	123	15.3	683	84.7
60–<70	941	38.4	261	27.7	680	72.3
>=70	1083	33.6	559	51.6	524	48.4
Race/Ethnicity
White	2118	37.5	743	35.1	1375	64.9	<0.0001
Black	234	41.5	40	17.1	194	82.9
Hispanic	365	38.6	118	32.3	247	67.7
API	520	44.7	59	11.3	461	88.6
Other	21	38.5	5	23.8	16	76.2
Stage
I	979	39.3	279	28.5	700	71.5	0.25
II	1030	38.4	325	31.5	705	68.5
III	1253	39.4	362	28. 9	891	71.1
Grade
Well differentiated	226	38.1	81	35.8	145	64.2	0.02
Moderate	2466	39.1	725	29.4	1741	70.6
Poor/Undiff	408	38.6	126	30.9	282	69.1
Unknown	162	41.4	34	21.0	128	79.0
Chemotherapy*
No	1559	37.8	537	34.4	1022	65.6	<0.0001
Yes	1703	40.2	429	25.2	1274	74.8
Radiation*
No	2755	38.5	863	31.3	1892	68.7	<0.0001
Yes	506	42.3	103	20.4	403	79.6
BMI
18.5–<25.0	1007	42.3	25	16.0	131	84.0	<0.0001
25.0–<30.0	1164	39.9	176	19.3	736	80.7
>=30.0	1030	34.6	223	57.9	162	42.1
Charlson comorbidity score
0	1770	41.0	380	21.7	1390	78.5	<0.0001
1–2	946	37.0	354	37.4	592	62.6
>=3	321	32.1	183	57.1	138	43.0
Missing	225	42.1	49	21.8	176	78.2
Cancer site
Proximal	1436	36.9	537	37.4	899	62.6	<0.0001
Distal	879	39.6	233	26.5	646	73.5
Rectal	947	41.8	196	20.7	751	79.3
Smoking
Never	1516	40.7	343	22.6	1173	77.4	<0.0001
Former	1347	37.4	495	36.7	852	63.2
Current	396	38.5	128	32.3	268	67.7
Muscle Tertiles
Low	1086	37.8	381	35.1	705	64.9	<0.0001
Middle	1088	39.5	309	28.4	779	71.6
High	1088	39.8	276	25.4	812	74.6
SF Tertiles
Low	1086	42.8	198	18.2	888	81. 8	<0.0001
Middle	1089	39.3	298	27.4	791	72.6
High	1087	35.0	470	43.2	617	56.8
VF Tertiles
Low	1087	44.6	127	11.74	960	88.3	<0.0001
Middle	1087	39.1	293	27.0	794	73.0
High	1088	33.4	546	50.2	542	49.8

^*Radiation and chemotherapy could be neoadjuvant or adjuvant.