Table 3.
Cross-classification of muscle radiodensity (HU) and sarcopenia
| Overall Mortality | CRC Mortality | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| At- risk |
Events | HR | Lower bound, 95% CI |
Upper bound, 95% CI |
Events | HR | Lower bound, 95% CI |
Upper bound, 95% CI |
|
| SMD and Sarcopenia | |||||||||
| Normal SMD, no sarcopenia | 1482 | 264 | Referent | 146 | Referent | ||||
| Normal SMD, sarcopenia | 814 | 217 | 1.30 | 1.07 | 1.57 | 113 | 1.42 | 1.09 | 1.84 |
| Low SMD, no sarcopenia | 397 | 142 | 1.63 | 1.30 | 2.05 | 62 | 1.57 | 1.13 | 2.20 |
| Low SMD, sarcopenia | 569 | 256 | 2.02 | 1.65 | 2.47 | 130 | 2.54 | 1.91 | 3.37 |
"SMD"=skeletal muscle radiodensity (HU); HR=hazard ratio
SMD and Sarcopenia model adjusted for visceral and subcutaneous adipose tissue in quartiles
Models additionally adjusted for age at diagnosis (continuous), sex (ref=Male), race (ref=White), site (ref=Proximal), stage (ref=I), grade (ref=well), chemotherapy (ref=No), radiation (ref=No), smoking history (ref=Never), comorbidity score (ref=0) and partitioned BMI (continuous)