Table 1.
Screening Strategies Evaluated by the Microsimulation Model
| Screening Modality | Age to Start Screening, Years | Age to Stop Screening, Years) | Screening Interval, Years | No. of (Unique) Strategiesa |
|---|---|---|---|---|
| No screening | 1 (1) | |||
| Colonoscopy | 40, 45, 50 | 75, 80, 85 | 5, 10, 15 | 27 (20) |
| Stool‐based tests | ||||
| Fecal immunochemical test | 40, 45, 50 | 75, 80, 85 | 1, 2, 3 | 27 (27) |
| High‐sensitivity guaiac‐based FOBT | 40, 45, 50 | 75, 80, 85 | 1, 2, 3 | 27 (27) |
| Multitarget stool DNA test | 40, 45, 50 | 75, 80, 85 | 1, 3, 5 | 27 (27) |
| Flexible sigmoidoscopy | 40, 45, 50 | 75, 80, 85 | 5, 10 | 18 (15) |
| Computed tomographic colonography | 40, 45, 50 | 75, 80, 85 | 5, 10 | 18 (15) |
| Total | 145 (132) |
Abbreviation: FOBT, fecal occult blood test.
a
The number of unique strategies excluded the strategies that overlap (eg, colonoscopy every 10 years from ages 50 to 80 years and from ages 50 to 85 years both include colonoscopies at ages 50, 60, 70, and 80 years and therefore are not unique strategies).