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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: J Cardiovasc Pharmacol. 2018 Jul;72(1):40–48. doi: 10.1097/FJC.0000000000000588

Figure 4. Hypertrophic and fibrotic response to 8 weeks treatment with tranilast.

Figure 4

Sham, TAC, and TAC tranilast posterior wall thickness (A) and LV mass/BW (B) was determined using echocardiography (*P<0.05 TAC compared to sham; §P<0.05 TAC tranilast compared to sham). HW/BW ratio (C) 8 weeks post-surgery (*P<0.05 compared to sham). Masson’s trichrome stained slides were used to determine the percentage of connective tissue (D, representative images E; *P<0.05 TAC compared to sham; **P<0.05 TAC versus TAC tranilast). P values are from two-way ANOVA RM (A and B) and one-way ANOVA (C and D).