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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Hepatology. 2018 May 10;68(1):304–316. doi: 10.1002/hep.29815

Figure 4. XBP1s protein and gene expression of Huh7-Ntcp and HepG2 cells treated with FXR agonists.

Figure 4

A) Huh7-Ntcp cells were treated with 6-ECDCA (0-10 μM) or DMSO vehicle for 4 hours and IRE1α, XBP1s, ERdj4 and SHP gene expression was measured with qPCR. B) Representative western blot of XBP1s is shown with GAPDH used as a loading control. C) HepG2 cells were treated with GW4064 (0-2.5 μM) or DMSO vehicle for 6 hours and IRE1α, XBP1s, ERdj4 and SHP gene expression was measured. D) Representative western blot of XBP1s is shown with β-actin used as a loading control. *P< 0.05, **P < 0.01, ***P < 0.001 compared to DMSO.