Skip to main content
. Author manuscript; available in PMC: 2019 Jul 9.
Published in final edited form as: Angew Chem Int Ed Engl. 2018 Jun 11;57(28):8664–8667. doi: 10.1002/anie.201804820

Figure 2.

Figure 2

(a) RhCl(PPh3)3, H2 (balloon), benzene, 23 °C, 18 h, 92% yield; (b) O3, pyridine, CH2Cl2, −78 °C, 4 min, 93% yield; (c) i. O3, pyridine, CH2Cl2, −78°C, 4 min, ii. p-TsOH, benzene, reflux, 18 h, 47% yield; (d) NaOH, EtOH/H2O (1:1), 60 °C, 18 h, 38% yield. 1:11 dr; (e) i. O3, MeOH, −78 °C, 0.5 h, ii. NaBH4, 0 °C, 3 h, 65% yield, 1:2.5 dr.