Table 2.
Pathways differentially regulated in astrocytes after EOD drinking.
| Database | Name | ID | #DE/# in category | p-value |
|---|---|---|---|---|
| KEGG | ECM-receptor interaction | Hsa04512 | 14/82 | 4.21e-06 |
| KEGG | cGMP-PKG signaling pathway | Hsa04022 | 19/167 | 4.11e-05 |
| KEGG | Focal adhesion | Hsa04510 | 20/202 | 1.83e-04 |
| KEGG | Vascular smooth muscle contraction | Hsa04270 | 13/120 | 1.03e-03 |
| KEGG | PI3-Akt signaling pathway | Hsa04151 | 26/341 | 1.32e-03 |
| WikiPathways | Calcium regulation in the cardiac cell | WP553 | 20/150 | 2.34e-06 |
| WikiPathways | Myometrial relaxation and contraction pathways | WP289 | 18/156 | 5.40e-05 |
| WikiPathways | Focal adhesion-Pi3K-Akt-mTOR signaling pathway | WP2841 | 26/303 | 2.26e-04 |
| WikiPathways | Focal adhesion | WP85 | 18/185 | 4.66e-04 |
| WikiPathways | Non-odorant GPCRs | WP1396 | 22/256 | 6.54e-04 |
| Reactome | Laminin organization | R-HSA-3000157 | 9/23 | 1.24e-07 |
| Reactome | Extracellular matrix organization | R-HSA-1474244 | 28/283 | 1.05e-05 |
| Reactome | Non-integrin membrane-ECM interactions | R-HSA-3000171 | 8/42 | 2.23e-04 |
| Reactome | ECM proteoglycans | R-HSA-3000178 | 9/55 | 3.05e-04 |
| Reactome | Integrin cell surface interactions | R-HSA-216083 | 10/62 | 3.12e-04 |