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. 2018 Jul 5;8:10175. doi: 10.1038/s41598-018-28490-y

Table 1.

Liver biochemistry in diminazene aceturate (DIZE) treated mice with biliary fibrosis.

Animal group Liver enzyme
ALT (U/L) AST (U/L) ALP (U/L)
Sham 12.58 ± 4.19 81.39 ± 22.57 46.85 ± 12.99
BDL + Saline 92.38 ± 32.66* 440.4 ± 139.27* 343.48 ± 91.8*
BDL + DIZE 57.11 ± 19.04*,# 307.2 ± 97.15*,# 254.7 ± 80.54*,#
Healthy control 18 ± 4.65 94.53 ± 24.41 30.13 ± 7.78
Mdr2-KO + Saline 152.47 ± 39.37* 405.47 ± 104.69* 231.8 ± 59.85*
Mdr2-KO + DIZE 79.71 ± 21.3*,# 250.14 ± 66.85*,# 149.83 ± 43.25*,#

Notes: *p < 0.05, significantly higher than respective sham or healthy control, #p < 0.05, significantly lower than respective saline infused mice.