Table 1.
Animal group | Liver enzyme | ||
---|---|---|---|
ALT (U/L) | AST (U/L) | ALP (U/L) | |
Sham | 12.58 ± 4.19 | 81.39 ± 22.57 | 46.85 ± 12.99 |
BDL + Saline | 92.38 ± 32.66* | 440.4 ± 139.27* | 343.48 ± 91.8* |
BDL + DIZE | 57.11 ± 19.04*,# | 307.2 ± 97.15*,# | 254.7 ± 80.54*,# |
Healthy control | 18 ± 4.65 | 94.53 ± 24.41 | 30.13 ± 7.78 |
Mdr2-KO + Saline | 152.47 ± 39.37* | 405.47 ± 104.69* | 231.8 ± 59.85* |
Mdr2-KO + DIZE | 79.71 ± 21.3*,# | 250.14 ± 66.85*,# | 149.83 ± 43.25*,# |
Notes: *p < 0.05, significantly higher than respective sham or healthy control, #p < 0.05, significantly lower than respective saline infused mice.