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Effect of ohrR deletion on avermectin production. (A) Avermectin production in ohrR-related mutants. (B) qRT-PCR of aveR and aveA1 transcription levels in WT, DohrR and CohrR. RNA samples as in Figure 1. ∗P < 0.05; ∗∗∗P < 0.001; NS, not significant (Student’s t-test).
