Table 6.
Change in mean vital signs from baseline to the end of study (90 days)
| Vital parameter | Supplements | Baseline | Day 90 (end of the study) | Change | p |
|---|---|---|---|---|---|
| Systolic blood pressure (mmHg) | B. coagulans MTCC 5856 | 122.5 | 121.0 | –1.50 | 0.2674 |
| Placebo | 123.5 | 120.0 | –3.50 | 0.0308 | |
| Diastolic blood pressure (mmHg) | B. coagulans MTCC 5856 | 77.0 | 79.5 | 2.50 | 0.1713 |
| Placebo | 80.5 | 80.0 | –0.50 | 0.7157 | |
| Pulse rate (beats per minute) | B. coagulans MTCC 5856 | 74.6 | 74.6 | 0.00 | 1.0000 |
| Placebo | 76.1 | 74.5 | –1.55 | 0.0841 | |
| Heart rate (beats per minute) | B. coagulans MTCC 5856 | 74.7 | 74.8 | 0.10 | 0.8660 |
| Placebo | 75.8 | 74.8 | –1.00 | 0.1467 | |
| Respiratory rate (breaths per minute) | B. coagulans MTCC 5856 | 21.1 | 21.1 | 0.00 | 1.0000 |
| Placebo | 21.4 | 20.8 | –0.60 | 0.1240 | |
| Weight (kg) | B. coagulans MTCC 5856 | 65.7 | 66.7 | 1.04 | 0.0589* |
| Placebo | 63.1 | 64.0 | 0.91 | 0.0785 | |
| Body mass index (kg/m2) | B. coagulans MTCC 5856 | 25.6 | 25.7 | 0.01 | 0.8956 |
| Placebo | 25.7 | 25.8 | 0.01 | 0.8969 |
*
p-value is estimated from paired t-test; p < 0.05 is considered as significant.