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. 2018 Jun 6;14:82–94. doi: 10.1016/j.molmet.2018.06.002

Figure 1.

Figure 1

N-acylethanolamine levels and ratios according to body mass index in premenopausal and menopausal women. Empty dots: premenopausal women. Solid dots: menopausal women. AEA: N-arachidonoylethanolamide; PEA: N-palmitoylethanolamide; OEA N-oleoylethanolamide; NW: normal weight; OW: overweight; OB: obese. AEA (A): aP = 0.011: OW vs. NW premenopausal women; bP < 0.001: OB vs. NW premenopausal women; cP = 0.026: OB vs. OW premenopausal women; dP = 0.004: OB vs. NW menopausal women. No significant differences were found by comparing OW vs. NW (P = 0.114) and OB vs. OW (P = 0.123) menopausal women. PEA (B): eP = 0.013: OW vs. NW premenopausal women; fP < 0.001: OB vs. NW premenopausal women. No significant differences were found by comparing OB vs. OW (P = 0.557) premenopausal women and by comparing pairs of BMI classes within menopausal women (OW vs. NW: P = 0.585; OB vs. NW: P = 0.074 and OB vs. OW: P = 0.176). OEA (C): gP = 0.012: OB vs. NW premenopausal women. No significant differences were found by comparing OW vs. NW (P = 0.118) and OB vs. OW (P = 0.587) premenopausal women and by comparing pairs of BMI classes within menopausal women (OW vs. NW: P = 0.362; OB vs. NW: P = 0.308, and OB vs. OW: P = 0.812). PEA/AEA (D): hP < 0.001: OB vs. NW premenopausal women; iP = 0.004: OB vs. OW premenopausal women; lP = 0.015: OB vs. NW menopausal women. No significant differences were found by comparing OW vs. NW (P = 0.280) premenopausal women and by comparing OW vs. NW (P = 0.070) and OB vs. OW (P = 0.366) menopausal women. OEA/AEA (E): mP < 0.001: OB vs. NW premenopausal women; nP = 0.001: OB vs. OW premenopausal women; oP = 0.012: OB vs. NW menopausal women. No significant differences were found by comparing OW vs. NW (P = 0.104) premenopausal women and by comparing OW vs. NW (P = 0.381) and OB vs. OW (P = 0.069) menopausal women. OEA/PEA (F): No significant differences were found by comparing pairs of BMI classes within premenopausal (OW vs. NW: P = 0.349; OB vs. NW: P = 0.257 and OB vs. OW: P = 0.967) and menopausal (OW vs. NW: P = 0.442; OB vs. NW: P = 0.427 and OB vs. OW: P = 0.137) women.