Figure 4.

Improvement in peak oxygen consumption (peak VO₂) with exercise training by rs3810 genotype. Improvement in peak VO₂ (mL/kg/min), measured as the difference in peak VO₂ before and after an exercise intervention, compared to rs3810 genotype. STRRIDE I and STRRIDE II datasets were combined for the analysis (GG genotype n = 168, GT genotype n = 207, TT genotype n = 90). The rs3810 genotype significantly predicted change in peak VO₂ (p = 0.0185), despite the fact that some groups differed in the intensity of the training stimulus.