Table 3.
Genotype association with risk of failure to complete study, controlling for race, gender, and intervention group.
| Additive Model | Dominant Model | ||||
|---|---|---|---|---|---|
| Odds Ratio | P-value | Odds Ratio | P-value | ||
| rs7844023 (C/T)* | STRRIDE I | 0.88 | 0.562 | 0.88 | 0.300 |
| STRRIDE II | 0.86 | 0.513 | 0.82 | 0.596 | |
| rs2898458 (A/G)* | STRRIDE I | 1.80* | 0.022* | 1.80 | 0.384 |
| STRRIDE II | 1.79* | 0.026* | 2.52* | 0.018* | |
| rs7508 (A/G)* | STRRIDE I | 1.17 | 0.546 | 1.17 | 0.499 |
| STRRIDE II | 1.78* | 0.034* | 2.55* | 0.015* | |
| rs3810 (G/T)* | STRRIDE I | 1.79* | 0.016* | 1.79 | 0.687 |
| STRRIDE II | 2.02* | 0.012* | 3.49* | 0.005* | |
| rs2427746 (A/G)* | STRRIDE I | 0.95 | 0.838 | 0.95 | 0.455 |
| STRRIDE II | 1.17 | 0.543 | 1.15 | 0.711 | |
| rs1049874 (T/C)* | STRRIDE I | 1.11 | 0.635 | 1.11 | 0.92 |
| STRRIDE II | 1.18 | 0.628 | 1.21 | 0.628 | |
All models controlled for race, gender and intervention group. Significant effects are marked with asterisk
(*)
and indicated in bold.