Table 6.
Children’s Hospital of Philadelphia Patients Only, Multivariable Model for ICU Mortality Including Data from Day 1 of Mechanical Ventilation (n = 427)
| Variable | Odds Ratio (95% CI) | P Value |
|---|---|---|
| PEEP lower than ARDSNet (vs. on-protocol/high PEEP) | 0.87 (0.32–2.35) | 0.78 |
| PRISM III* | 1.10 (1.07–1.14) | <0.001 |
| Immunodeficiency (vs. no immunodeficiency) | 2.80 (1.26–6.24) | 0.012 |
| Stem cell transplant (vs. no stem cell transplant) | 4.70 (1.69–13.2) | 0.003 |
| PF ratio (Day 1)* | 0.995 (0.989–1.0001) | 0.06 |
For definition of abbreviations, see Table 5.
PEEP lower than recommended by the ARDS Network Protocol for a given FiO2 did not remain independently associated with mortality after multivariable adjustment.
*
Variables treated as continuous in the multivariable model.