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. 2018 Jul 7;24(25):2733–2740. doi: 10.3748/wjg.v24.i25.2733

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©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Increase of transforming growth factor-β+ regulatory cells in the serum of hepatocellular carcinoma patients. A: Representative plots for identification of the TGF-β+ Treg cells producing cells in PBMC; B: Analysis of the frequency of TGF-β+ Treg cell from the PBMCs of healthy donors in comparison to HCC patients; C: Analysis of the frequency of TGF-β+ Treg cell from the PBMCs of healthy donors in comparison to HCC patients with tumors at different stages. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. TGF-β: Transforming growth factor-β; Treg: Regulatory cells; PBMC: Peripheral blood mononuclear cells; HCC: Hepatocellular carcinoma.