Fig. 3. Nanodiamonds were internalized into cells over time in two different breast cancer cell lines: (a) MDA-MB-231 and (b) MCF-7 cells. ‘Total area per cell’ refers to the total nanodiamond intracellular area in the images divided by the number of nuclei observed in that image. Oxidized diamonds were taken up in a greater amount than graphitic diamonds (p = 4 × 10–8 for MDA-MB-231s and p = 3 × 10–5 for MCF-7s). NBiologicalreplicates = 2 (control) and 3 (nanodiamond sample). NNuclei = 500 ± 200 per condition for MDA-MB-231 and 430 ± 170 per condition for MCF-7.
