Table 2. Binding Parameters Calculated From ITC Measurements for each M13 Variant Peptide with CaMa.
peptide | Kd (μM) | ΔH (kJ/mol) | n |
---|---|---|---|
M13 | 0.5 | –59 | 0.9 |
W4C* | 0.3 | –43 | 0.9 |
F8C* | 1.1 | –27 | 0.9 |
0.02 | –26 | 0.3 | |
S12C* | 2 | –64 | 1.0 |
R16C* | 2 | –32 | 1.1 |
I20C* | 1.4 | –72 | 1.0 |
S23C* | 3 | –65 | 1.0 |
See the Supporting Information for the data and details of these fits.