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. 2018 Jul 5;49:57. doi: 10.1186/s13567-018-0552-8

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Protection efficacies of four rough ST-based LI vaccines. All the immunized and control mice groups were challenged with 10^6.9TCID₅₀ LI strains at week 8 post-immunization. Protection shown by a cocktail of all the four strains. The protection against LI was assessed based on the presence of gDNA in stool samples. Protection is presented as the number of animals showing gDNA in stool samples to the total number of animals in that group. Five animals were sacrificed at each time-point indicated.