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. 2018 Jul 5;10:92. doi: 10.1186/s13148-018-0523-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Prognostic and predictive value of SOX30 methylation in MDS/AML patients. a–f The prognostic value of SOX30 methylation for OS and LFS among AML patients. The survival analysis was performed among different subtypes of AML patients included whole-cohort AML, non-M3-AML, and CN-AML patients. g Dynamic changes of SOX30 methylation level in paired MDS/sAML patients. SOX30 methylation level was examined by RQ-MSP. sAML indicated MDS-derived AML patients. h, i The prognostic value of SOX30 methylation for OS and LFS among MDS patients