Fig. 6.
Ischemic preconditioning (IP) and IP + carbenoxolone increased efficient excitatory amino acid transporter 1 expression in astrocytes following oxygen-glucose deprivation/re-oxygenation. Real time PCR for excitatory amino acid transporter 1 (EAAT1) mRNA. The relative expression of EAAT1 mRNA in all samples was quantified in comparison with glyceraldehyde 3-phosphate dehydrogenase (GAPDH). Levels of EAAT1 mRNA expression were reduced following oxygen-glucose deprivation/re-oxygenation (OGD/R). However, this trend is mitigated by ischemic preconditioning (IP) and IP + carbenoxolone (CBX)