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. 2017 Aug 28;2(4):418–430. doi: 10.1016/j.jacbts.2017.06.005

Table 2.

Effect of 2-Day Gevokizumab Treatment in Goto-Kakisaki Rats

Ischemia/Reperfusion
Untreated Gevokizumab Treated
LV weight, g 0.90 ± 0.02 0.86 ± 0.01
Area at risk, % of LV 43.4 ± 3.0 45.2 ± 4.9
Infarct size, % of LV 16.6 ± 1.8 7.6 ± 1.9
LV ESP, mm Hg 93.9 ± 6.8 90.0 ± 5.2
LV ESPVR, mm Hg/RVU 12.5 ± 1.0 16.4 ± 1.0
LV EDP, mm Hg 2.06 ± 0.31 1.27 ± 0.15
LV EDPVR, mm Hg/RVU 2.15 ± 0.21 1.44 ± 0.17

Values are mean ± SD.

Abbreviations as in Table 1.

p <0.05 versus untreated I/R. n = 10 to 15 per group.