Table 1.

Baseline characteristic data for patients with a repeated fungal culture performed 6 days after enrollment and treatment in the MUTT-II trial (N=208). Continuous variables

Baseline Characteristic	Fungal Culture Positive on Day 6 (N=100)	Fungal Culture Negative on Day 6 (N=108)	P5
Sex, N
Male	47	59	0.01
Female	44	43
Age (years), mean (sd)	51.4 (12.8)	52.9 (12.8)	0.41
Occupation, N		55 (46, 60)
Agriculture	38	35	0.37
Non-Agriculture1	55	67
Medication use at enrollment2, N
Topical ocular antifungals	56	54	0.32
Other topical ocular drops3	47	50	0.89
Systemic antifungals	6	8	0.78
Other systemic	21	20	0.73
Trauma/Injury, N
Vegetative Matter/Wood	26	39	0.14
Metal/Other4	27	24	0.52
Unknown Object	2	0	0.23
Contact Lens	0	0	1
Affected Eye, N
Right	55	55	0.47
Left	38	47
Visual Acuity (logMAR), mean (sd)	1.57 (0.36)	1.53 (0.37)	0.21
Infiltrate/Scar Size (mm1), mean (sd)	5.69 (1.49)	5.41 (1.67)	0.22
Presence of Hypopyon
no	25	30	0.75
yes	67	70
Depth
>0–33%	19	33
>33–67%	44	46	0.10
>67–100%	36	28
Epithelial Defect (mm1), mean (sd)	4.92 (1.80)	4.44 (1.82)	0.06
Duration of Symptoms, days, median (25th, 75th percentiles)	10(5,15)	9 (7,15)	0.79
Day 6 Clinical Characteristics	Fungal Culture Positive on Day 6 (N=91)	Fungal Culture Negative on Day 6 (N=97)	P5
Infiltrate/Scar Size (mm1), mean (sd)	5.72 (1.58)	5.21 (1.75)	0.04
Presence of Hypopyon
no	27	48	0.004
yes	64	47
Depth
>0–33%	16	33
>33–67%	38	32	0.03
>67–100%	37	32
Epithelial Defect (mm1), mean (sd)	4.45	3.8	0.02

¹Includes unemployed, retired, etc.

²Some patients were on more than one medication at enrollment

³Includes topical antibiotics, dilating drops, glaucoma medication, lubricating drops

⁴Includes dust, finger, kerosene, cement, fingernail, chili powder, sand, cow’s tail, insect

⁵The P value for age was calculated using Wilcoxon rank sum test. All other continuous variables used t-test and categorical variables the Fisher’s exact test.