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. 2018 Jul 5;11(4):1044–1052. doi: 10.1016/j.tranon.2018.06.008

Figure 2.

Figure 2

In vivo time-dependent fluorescence images of HCT116 tumor-bearing mouse using PSP1. (A) PSP1-flamma675 or control peptide-flamma675 was injected into the tail vein of mice after receiving radiation therapy 10 Gy to tumor area. The yellow arrows indicate the tumors. (B) Ex vivo fluorescence images of major organs and tumors from PSP1-treated mouse after excision at 24 hours postinjection of PSP1. (C) Quantification of fluorescence intensities of excised tumor. Li = liver; Spl = spleen; Ki = kidney; Hr = Heart; Lu = Lung; Tu = Tumor. The results are expressed as the mean ± SD from three independent experiments. Asterisks represent statistical significance compared to control group. Asterisks on brackets represent significance in difference between the two groups. *P < .05 and **P < .01 by one-way ANOVA.