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. 2018 Jul 5;11(4):1044–1052. doi: 10.1016/j.tranon.2018.06.008

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© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Comparison of a single-dose and multifractionated doses of irradiation in mice administered with PSP1-flamma675. (A) Radiation therapies of 10 Gy, 5 Gy × 2 times, 5 Gy × 1 time, and 2 Gy × 5 times to right legs [IR (+)] are followed by administration of PSP1-flamma675 or control peptide-flamma675 to mice. The yellow arrows indicate the tumors. (B) Quantification of fluorescence signal intensity in mice after administration of PSP1-flamma675. Asterisks represent statistical significance compared to control group. Asterisks on brackets represent significance in difference between the two groups. *P < .05 and ***P < .001 by one-way ANOVA.