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. 2018 Jul 3;6:e5118. doi: 10.7717/peerj.5118

Figure 1. The percentage of rare and common 5-mers in DQ- and DR-associated epitopes.

Figure 1

The figures show the fraction of 5-mers found for certain times in the human proteome. DQ-associated epitopes contained (A) less rare 5-mers and (B) a higher number of common 5-mers than DR-associated sequences. 5-mer composition of 815 human epitopes (green) is also shown on the figures. Dashed lines represent different cutoffs used for defining (A) rare 5-mers and (B) common 5-mers. P values represent the probability of having the same or higher difference between the number of rare and common 5-mers in DQ and DR-associated epitopes by chance (see Methods). Note that in case of common alleles, both horizontal and vertical axes were log-transformed for better visualization.