Table 2. Mortality (%) and malformations (%) in chicken embryos after in ovo exposure to tamoxifen (Tam, 0, 1, 1, 10 µg/g egg) and EE2 (20 ng/g egg) or co-exposure to all concentrations of tamoxifen (plus 0.001, 0.01 µg/g egg) and EE2.
| Test substance | Tamoxifen | |||
|---|---|---|---|---|
| ∑ experiments | 4 | |||
| ∑ eggs | 603 | |||
| Group | ∑ eggs | ∑ fertilized eggs | Mortality (%)a | Malformations (%)a |
| NC | 93 | 88 | 7.95 (7) | 0.00 (0) |
| SC | 83 | 75 | 28.0 (21) | 5.33 (4) |
| Tam 0.1 | 60 | 53 | 43.4 (23) | 5.66 (3) |
| Tam 1 | 60 | 51 | 39.2 (20) | 1.96 (1) |
| Tam 10 | 59 | 52 | 55.8 (29) | 1.92 (1) |
| EE2 | 47 | 45 | 24.4 (11) | 6.67 (3) |
| Tam 0.001 +EE2 | 30 | 28 | 7.14 (2) | 7.14 (2) |
| Tam 0.01 +EE2 | 31 | 30 | 20.0 (6) | 3.33 (1) |
| Tam 0.1 +EE2 | 46 | 44 | 34.1 (15) | 4.54 (2) |
| Tam 1 +EE2 | 47 | 45 | 40.0 (18) | 4.44 (2) |
| Tam 10 +EE2 | 47 | 43 | 30.2 (13) | 6.98 (3) |
Notes.
a
The number in parentheses represents the number of affected embryos.
TITLE
- NC
- untreated control
- SC
- solvent control