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. Author manuscript; available in PMC: 2018 Jul 6.
Published in final edited form as: J Clin Lipidol. 2018 Mar 2;12(3):718–727.e6. doi: 10.1016/j.jacl.2018.02.010

Table S3. Risk of events by Omega-3 Index modified to include docosapentaenoic acid (n = 2500).

Hazard ratios (95% CIs
Total CVD Total CHD Total stroke Any mortality
Omega-3 Index–adjusted
 <4.2% (n = 508) 1.0 1.0 1.0 1.0
 4.2%–4.9% (n = 500) 1.06 (0.69, 1.63) 1.05 (0.60, 1.83) 1.16 (0.60, 2.24) 0.74 (0.53, 1.04)
 4.9%–5.7% (n = 501) 1.10 (0.72, 1.68) 0.81 (0.44, 1.48) 1.30 (0.68, 2.49) 0.67 (0.46, 0.96) *
 5.7%–6.8% (n = 502) 0.74 (0.47, 1.17) 0.63 (0.34, 1.20) 0.59 (0.28, 1.25) 0.59 (0.41, 0.86)
 >6.8% (n = 489) 0.61 (0.37, 0.99) * 0.58 (0.29, 1.18) 0.45 (0.20, 1.03) 0.66 (0.45, 0.96) *
P-value for linear trend .008 .03 * .006 .02 *
Modified Omega-3 Index (+DPA)–adjusted
 <6.7% (n = 510) 1.0 1.0 1.0 1.0
 6.7%–7.5% (n = 497) 1.01 (0.66, 1.54) 0.93 (0.54, 1.61) 1.04 (0.52, 2.07) 0.75 (0.53, 1.06)
 7.5%–8.4% (n = 502) 0.83 (0.54, 1.27) 0.58 (0.32, 1.05) 1.09 (0.57, 2.08) 0.48 (0.40, 0.84)
 8.4%–9.7% (n = 507) 0.69 (0.44, 1.08) 0.54 (0.29, 1.01) 0.65 (0.31, 1.35) 0.72 (0.50, 1.04)
 >9.7% (n = 484) 0.64 (0.40, 1.03) 0.54 (0.27, 1.05) 0.51 (0.23, 1.14) 0.61 (0.41, 0.90) *
P-value for linear trend .012 * .013 * .024 * .02 *

CVD, cardiovascular disease; CHD, coronary heart disease; CI, confidence interval.

*

P < .05

P < .01

P < .001.

All significant hazard ratios/P-values are shown in bold italics.

Adjusted for all variables in Table 1.