Table S3. Risk of events by Omega-3 Index modified to include docosapentaenoic acid (n = 2500).
| Hazard ratios (95% CIs |
||||
|---|---|---|---|---|
| Total CVD | Total CHD | Total stroke | Any mortality | |
| Omega-3 Index–adjusted | ||||
| <4.2% (n = 508) | 1.0 | 1.0 | 1.0 | 1.0 |
| 4.2%–4.9% (n = 500) | 1.06 (0.69, 1.63) | 1.05 (0.60, 1.83) | 1.16 (0.60, 2.24) | 0.74 (0.53, 1.04) |
| 4.9%–5.7% (n = 501) | 1.10 (0.72, 1.68) | 0.81 (0.44, 1.48) | 1.30 (0.68, 2.49) | 0.67 (0.46, 0.96) * |
| 5.7%–6.8% (n = 502) | 0.74 (0.47, 1.17) | 0.63 (0.34, 1.20) | 0.59 (0.28, 1.25) | 0.59 (0.41, 0.86) † |
| >6.8% (n = 489) | 0.61 (0.37, 0.99) * | 0.58 (0.29, 1.18) | 0.45 (0.20, 1.03) | 0.66 (0.45, 0.96) * |
| P-value for linear trend | .008 † | .03 * | .006 † | .02 * |
| Modified Omega-3 Index (+DPA)–adjusted | ||||
| <6.7% (n = 510) | 1.0 | 1.0 | 1.0 | 1.0 |
| 6.7%–7.5% (n = 497) | 1.01 (0.66, 1.54) | 0.93 (0.54, 1.61) | 1.04 (0.52, 2.07) | 0.75 (0.53, 1.06) |
| 7.5%–8.4% (n = 502) | 0.83 (0.54, 1.27) | 0.58 (0.32, 1.05) | 1.09 (0.57, 2.08) | 0.48 (0.40, 0.84) † |
| 8.4%–9.7% (n = 507) | 0.69 (0.44, 1.08) | 0.54 (0.29, 1.01) | 0.65 (0.31, 1.35) | 0.72 (0.50, 1.04) |
| >9.7% (n = 484) | 0.64 (0.40, 1.03) | 0.54 (0.27, 1.05) | 0.51 (0.23, 1.14) | 0.61 (0.41, 0.90) * |
| P-value for linear trend | .012 * | .013 * | .024 * | .02 * |
CVD, cardiovascular disease; CHD, coronary heart disease; CI, confidence interval.
P < .05
P < .01
P < .001.
All significant hazard ratios/P-values are shown in bold italics.
Adjusted for all variables in Table 1.