Table 2.
Univariate analysis comparing subjects with and without hematoma expansion
| Hematoma Expansion | |||
|---|---|---|---|
| YES (n=62) | NO (n=282) | p | |
| Age, mean (SD) | 70.0 (13.9) | 70.1 (13.6) | 0.99 |
| Sex, n (%) | 0.38 | ||
| Male | 37 (59.7) | 151 (53.5) | |
| Female | 25 (40.3) | 131 (46.5) | |
| Hypertension, n (%) | 49 (79.0) | 232 (82.3) | 0.72 |
| Admission SBP, mean (SD) | 177.7 (40.3) | 182.5 (34.8) | 0.40 |
| Admission DBP, mean (SD) | 94.8 (25.4) | 97.6 (26.1) | 0.45 |
| Admission INR, mean (SD) | 1.0 (0.1) | 1.1 (0.1) | 0.45 |
| Antiplatelet treatment, n (%) | 33 (53.2) | 117 (41.5) | 0.08 |
| Baseline ICH volume, median (IQR) | 14.0 (7.0-27.5) | 23.2 (10.4-38.3) | 0.003 |
| ICH location | 0.75 | ||
| Deep, n (%) | 42 (67.7) | 185 (65.6) | |
| Lobar, n (%) | 20 (32.3) | 97 (34.4) | |
| GCS, median (IQR) | 13.0 (10.0-15.0) | 14.0 (10.0-15.0) | 0.42 |
| IVH, n (%) | 26 (41.9) | 118 (41.8) | 0.99 |
| Time from onset to NCCT scan, | |||
| Median, (IQR), h | 1.8 (1.2-3.5) | 3.4 (2.0-5.0) | <0.0001 |
| <2.5 h, n (%) | 36 (58.1) | 70 (24.8) | <0.0001 |
| >2.5 h, n (%) | 16 (25.8) | 130 (46.1) | |
| Unknown, n (%) | 10 (16.1) | 82 (29.1) | |
| Hypodensities, n (%) | 33 (53.2) | 51 (18.1) | <0.0001 |
| Blend Sign, n (%) | 17 (27.4) | 37 (13.1) | 0.005 |
| Irregular Shape, n (%) | 36 (58.1) | 124 (44.0) | 0.044 |
| Heterogeneous Density, n (%) | 25 (40.3) | 42 (14.9) | <0.0001 |
| Fluid Level, n (%) | 2 (3.2) | 14 (5.0) | 0.56 |
| 90-day Mortality, n (%) | 29 (46.8) | 53 (18.8) | <0.0001 |
SD indicates standard deviation; SBP, systolic blood pressure; DBP, diastolic blood pressure; INR, International normalized ratio; ICH, intracerebral hemorrhage; GCS, Glasgow coma scale; IVH, intraventricular hemorrhage; IQR, interquartile range.