Table 2.
Group | n | 20 mmHg | 40 mmHg | 60 mmHg | 80 mmHg |
---|---|---|---|---|---|
NH | 8 | 0.75 ± 0.25 | 1.25 ± 0.25 | 2.00 ± 0.27 | 2.25 ± 0.25 |
NMS + RS | 8 | 1.13 ± 0.30 | 2.63 ± 0.32a | 3.00 ± 0.27b | 3.25 ± 0.25b |
High dose | 8 | 1.00 ± 0.27 | 1.5 ± 0.33d | 2.00 ± 0.27d | 2.38 ± 0.38d |
Middle dose | 8 | 1.00 ± 0.27 | 1.38 ± 0.32d | 2.13 ± 0.35d | 2.38 ± 0.32d |
Low dose | 8 | 1.00 ± 0.27 | 1.88 ± 0.40 | 2.88 ± 0.30b | 3.25 ± 0.25b |
Pinaverium bromide | 8 | 1.00 ± 0.27 | 1.38 ± 0.32d | 2.00 ± 0.27d | 2.25 ± 0.25d |
P < 0.01,
P < 0.05, versus the normal control (no handling [NH]) group.
P < 0.01,
P < 0.05, versus the neonatal maternal separation (NMS) + restraint stress (RS) group.
Data are expressed as the mean ± SE (n = 8 rats/group).