Figure 4.
c-Fos protein expression in the PL and IL of female rats that had been exposed to post-weaning social isolation (PSI) or social rearing (SR) for 4 weeks, then either 0 mg/kg (vehicle), 1 mg/kg, or 5 mg/kg MJN110. Two hr later rats were exposed to a novel same-sex rat for 15 min. There were no differences between groups in the PL (top). In the IL (bottom), there was no effect of rearing condition, but there was a significant Social × Drug effect. The inset shows c-fos in the IL collapsed over Rearing condition. * p < 0.05. Data are means ± SEMs.