Table 3. Clinical responses per RECIST and clinical benefit rate based on age.
| AYA (15–39 y) | Middle age (40–64 y) | Older Adults (65+y) | Total | |
|---|---|---|---|---|
| Total number of patients | 220 | 991 | 278 | 1489 |
| Complete response (CR) | 2 (1%) | 6 (1%) | 0 (0%) | 8 (<1%) |
| Partial response (PR) | 34 (16%) | 101 (10%) | 23 (8%) | 158 (11%) |
| Stable disease (SD) <6 months | 51 (23%) | 289 (29%) | 83 (30%) | 423 (28%) |
| Prolonged SD >6 months | 42 (19%) | 211 (21%) | 53 (19%) | 306 (21%) |
| Progressive disease | 91 (41%) | 384 (39%) | 119 (43%) | 594 (40%) |
| Clinical benefit rate (CBR) | 78 (35%) | 318 (32%) | 76 (27%) | 472 (32%) |
Abbreviations: AYA Adolescent and young adults. CBR Clinical benefit rate ([CR + PR + SD > 6 m]/number of patients in that age cohort).