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. 2018 Jun 22;9(48):28935–28950. doi: 10.18632/oncotarget.25649

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Copyright: © 2018 Yoshii et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A) OpenPET system used for the surgical procedures. (B) Representative images of mice bearing transplanted HCT116-RFP tumors at deep sites during OpenPET-guided surgery. A series of images taken during OpenPET-guided surgery is shown, including pre-operation (left), opening the abdomen (middle), and tumor isolation while checking real-time OpenPET images (right) (see details in Supplementary Video 1). (C, D) OpenPET images. (C) A tumor (approximately 10 mm) located behind the intestine in the middle of peritoneal cavity is shown. (D) A small (3-mm) tumor located deeply in the peritoneal cavity is shown.